解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::GABA release was recorded in vivo by push-pull perfusion from the globus pallidus and substantia nigra of control rats, rats with unilateral ibotenic acid lesions of the neostriatum, and rats with embryonic striatal tissue grafts implanted in the lesioned striatum. The lesions reduced baseline levels of GABA release t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90068-1
更新日期:1988-03-01 00:00:00
abstract::Exposure of male Syrian hamsters to a short daylength of 8L:16D leads to gonadal regression. This effect of photoperiod was prevented by pinealectomy or chronic exposure of the brain to exogenous melatonin delivered from in-dwelling cannulae. However, the effect of melatonin was dependent on the neural site of applica...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90081-4
更新日期:1988-03-01 00:00:00
abstract::The responses of non-dopamine neurons in substantia nigra and ventral tegmental area to systemic amphetamine were investigated in the behaving rat chronically implanted with multiple fine-wire electrodes. The neurons were identified with electrophysiological criteria requiring that the signals be of biphasic shape, sh...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90343-0
更新日期:1988-02-01 00:00:00
abstract::The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90365-x
更新日期:1988-02-01 00:00:00
abstract::Co-localization of neurotensin and cholecystokinin in tyrosine hydroxylase-containing neurons in the nucleus tractus solitarius of the rat was demonstrated by immunocytochemistry with fluorescent double-staining combined with the peroxidase-antiperoxidase method. Co-localization of neurotensin/tyrosine hydroxylase or ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90326-0
更新日期:1988-01-01 00:00:00
abstract::The neurochemical and behavioural recovery following unilateral and bilateral lesions of the nucleus basalis was investigated in adult male Wistar rats 20 days and 6 months after surgery. The lesions were made by stereotaxic injections of ibotenic acid. Twenty days after surgery there was a statistically significant c...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90324-7
更新日期:1988-01-01 00:00:00
abstract::On mating with a stud male, virgin female mice from an olfactory memory to this male which is essential to their reproductive success. Failure to form this memory results in the stud male being treated as strange, and hence, his pheromones block pregnancy. This study investigates the duration of the olfactory memory, ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(88)90314-4
更新日期:1988-01-01 00:00:00
abstract::This study examines the proposal that striatonigral pathways support circling mediated by dopamine D1 receptors, but not D2 receptors, in unilaterally 6-hydroxydopamine-treated rats. In this model the D1/D2 agonist apomorphine, the D1 agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine hydrochloride and...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90175-8
更新日期:1987-12-01 00:00:00
abstract::An original pathway of centrifugal acetylcholinesterase-positive fibres is described in the olfactory bulb of the rat. A dense network of positive fibres spreads out superficially at the boundaries of the lateral olfactory tract and the glomerular layer. These labelled fibres converge towards atypical glomerular struc...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90183-7
更新日期:1987-12-01 00:00:00
abstract::The distribution of peptide histidine-isoleucine (PHI) and vasoactive intestinal polypeptide (VIP), two peptides derived from the same precursor molecule, was analysed with immunohistochemistry in the central nervous system of the rat, and to a limited extent in some other species including sheep, monkey and man. Spec...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90162-x
更新日期:1987-12-01 00:00:00
abstract::Loyez' myelin stain sometimes impregnates the perikarya and processes of neurons. This is rare in normal adult mice, but can be provoked by various means including electrical stimulation and mild ischaemia shortly before fixation. Passing a direct current or a train of pulses across the dura of the cerebral cortex pro...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90172-2
更新日期:1987-12-01 00:00:00
abstract::Isolated neurointermediate lobes or neural lobes of the rat pituitary gland attached to the pituitary stalk were incubated in vitro and the spontaneous or electrically (pituitary stalk stimulation, 5 Hz, 1,500 pulses) evoked release of 5-hydroxytryptamine was determined. The evoked release of 5-hydroxytryptamine from ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90085-6
更新日期:1987-11-01 00:00:00
abstract::The intense immunohistochemical reaction for the enzyme adenosine deaminase displayed by neurons in the tuberomammillary nucleus in the rat was used to study the distribution and morphology of cells comprising this nucleus, their fiber fields within the posterior hypothalamus and their projection pathways from the hyp...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90077-7
更新日期:1987-11-01 00:00:00
abstract::The effects of steady iontophoretic applications of serotonin on the spontaneous discharge and on the excitatory responses induced in deep cerebellar nuclei neurons by iontophoretic pulse applications of L-glutamate, L-aspartate, N-methyl-D,L-aspartate and quisqualate were studied in rat cerebellar slices maintained i...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90072-8
更新日期:1987-11-01 00:00:00
abstract::Miniature endplate potentials were recorded from the isolated pectoralis cutaneous muscle of the frog during very stable recording conditions and low noise levels. Two to 5 x 10(3) miniature endplate potentials were filmed at eight unstressed junctions that met rigorous experimental criteria for analysis. Seven juncti...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90093-5
更新日期:1987-11-01 00:00:00
abstract::Neurons depend upon the processes of axonal and transneuronal transport for intra- and intercellular communication and trophic support. Experimental studies in the last decade have elucidated the mechanisms underlying these processes, and provided evidence for their role in the spread of viral and toxic diseases throu...
journal_title:Neuroscience
pub_type: 杂志文章,评审
doi:10.1016/0306-4522(87)90063-7
更新日期:1987-11-01 00:00:00
abstract::Specific high-affinity neurotensin binding sites were labeled in sections of the rat caudal brainstem using a monoiodinated ligand, and their distribution was examined by light microscopic radioautography after fixation with glutaraldehyde. In the medulla, labeled binding sites were mainly concentrated within the dors...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90282-x
更新日期:1987-10-01 00:00:00
abstract::The effect of pairing two vibrissa stimulations on unit responses of the barrel field of the somatosensory cortex were studied in partially restrained but awake and undrugged rats. Before pairing, one of the stimulations (S2) evoked a stable, short-latency and excitatory response from the recorded unit. Depending on t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90271-5
更新日期:1987-10-01 00:00:00
abstract::The uptake and transport of basic and acidic horseradish peroxidase isoenzymes was compared in the neuromuscular, visual and olfactory systems of Xenopus larvae and postmetamorphic frogs. The concentration (w/v) of the two preparations was corrected to compensate for their difference in enzymatic activity (unit/w), wh...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)92988-5
更新日期:1987-09-01 00:00:00
abstract::The synaptic organization of terminals originating either from the spinal cord (spinothalamic) or from the dorsal column nuclei (lemniscal) was investigated in the ventrobasal complex of the rat thalamus. Wheatgerm agglutinin conjugated to horseradish peroxidase was used as an anterogradely transported axonal tracer, ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)92970-8
更新日期:1987-09-01 00:00:00
abstract::The distribution of adenosine A1 receptors was studied quantitatively in the brain of the rat, mouse, guinea-pig and cat, using in vitro autoradiography with [3H]N6-cyclohexyladenosine as ligand. Preliminary binding studies in brain sections from the guinea-pig and cat gave results similar to previous data from the ra...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)92961-7
更新日期:1987-09-01 00:00:00
abstract::A new double-label autoradiographic glucose analog method for the sequential measurement of altered regional cerebral metabolic rates for glucose in the same animal is presented. This method is based on the sequential injection of two boluses of glucose tracer labeled with two different isotopes (short-lived 18F and l...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90357-5
更新日期:1987-08-01 00:00:00
abstract::The neuronal uptake and laminar distribution of cortically injected tritium-labeled gamma-aminobutyrate (GABA), aspartic acid, glutamate and glycine was examined in the prestriate cortex of squirrel monkeys. The intent of this investigation was not to examine the role of these amino acids as neurotransmitters, but to ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90343-5
更新日期:1987-08-01 00:00:00
abstract::The presynaptic changes caused by 4-aminopyridine were studied in the electric organ of Torpedo marmorata, in the resting state and during the period following transmission of a single giant discharge. Incubation with 4-aminopyridine provoked a 30-40% decrease in the density of synaptic vesicles in nerve terminals, an...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90367-8
更新日期:1987-08-01 00:00:00
abstract::The generation of long-term potentiation of synaptic transmission in area CA1 of hippocampal slices of the guinea-pig has been examined in solutions containing low concentrations of magnesium ions. It was found that the induction of long-term potentiation is greatly facilitated in slices perfused with 0.1 mM magnesium...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90193-x
更新日期:1987-07-01 00:00:00
abstract::The distribution of atrial natriuretic factor-like immunoreactivity in the central nervous system of the frog Rana ridibunda was investigated by indirect immunofluorescence and the immunogold technique, using an antiserum generated in rabbits against synthetic atrial natriuretic factor (Arg 101-Tyr 126). A stereotaxic...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90225-9
更新日期:1987-07-01 00:00:00
abstract::Studies were made on the effect of the neuroexcitatory agent kainic acid, microinjected into raphe dorsal nucleus by glass micropipette and an air pressure system in doses ranging from 0.2 to 24.0 nmol (in volumes from 0.05 microliter to 0.47 microliter), on the somatosensory evoked potentials and their cycles of reco...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90199-0
更新日期:1987-07-01 00:00:00
abstract::I have prepared a number of monoclonal antibodies to chromaffin cell membranes. One of these antibodies recognizes a number of antigenically related proteins that are present in all tissues examined. In the adrenal, these proteins are completely excluded from chromaffin granules but are present in other subcellular me...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90204-1
更新日期:1987-07-01 00:00:00
abstract::Experiments in a variety of preparations have indicated that excessive activation of receptors for the excitatory amino acids glutamate and aspartate may mediate irreversible anoxic neuronal injury. We investigated this hypothesis in the in vitro hippocampal slice. Rat hippocampal slices perfused for 40 min with buffe...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90027-3
更新日期:1987-06-01 00:00:00
abstract::The hypothesis that electrotonic spread among oxytocinergic neurons contributes to synchronized bursting in the lactating rat leads to the prediction that coupling among oxytocinergic neurons would be stronger and more abundant in lactating than in non-lactating animals. We tested this prediction using, as an index of...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90047-9
更新日期:1987-06-01 00:00:00
abstract::It was demonstrated with autoradiographic methods that a tract of thin fibers, which is for the most part distinct from the brachium conjunctivum and its crossed descending limb, can be followed from the cerebellar nuclei to the inferior olive. Neurons from all regions of the interposed and dentate nuclei contribute t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90044-3
更新日期:1987-06-01 00:00:00
abstract::The distribution of the C-terminal glycopeptide of the vasopressin prohormone was mapped in rat brain by an immunocytochemical method using antibodies to the sheep glycopeptide. The antibodies did not react with vasopressin, oxytocin or their related neurophysins. Stained neural perikarya were observed in the hypothal...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90046-7
更新日期:1987-06-01 00:00:00
abstract::Specific acetylcholinesterase and non-specific cholinesterases are present in all three lobes of the rat pituitary gland. This paper describes two new observations on hypophyseal acetylcholinesterase. Firstly, a prolonged increase of neurohormone secretion evoked by dehydration and sodium loading was accompanied by a ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90132-1
更新日期:1987-05-01 00:00:00
abstract::The effect of the intrathecal administration of the catecholaminergic neurotoxin 6-hydroxydopamine, or of hemisection of the spinal cord at the Cl level, on the density of alpha 2-adrenoceptors and on the norepinephrine, dopamine, and serotonin content in the cat lumbar spinal enlargement was determined 2, 7 or 21 day...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90128-x
更新日期:1987-05-01 00:00:00
abstract::The ultrastructural features and synaptic contacts of two types of neurotensin-containing amacrine cells in turtle retina were examined by electron immunocytochemistry, and the retinal peptides were characterized using radioimmunoassay and high-pressure liquid chromatography. The two types of cell were distinguished o...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90146-1
更新日期:1987-05-01 00:00:00
abstract::Serotonin and gamma-aminobutyric acid (GABA) neurons in the nucleus raphe dorsalis were identified by immunocytochemistry using antibodies to 5-hydroxytryptamine or GABA. The pattern of the 5-hydroxytryptamine and GABA immunostaining presented similar features: 5-hydroxytryptamine or GABA immunoreactive somata were fu...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90336-8
更新日期:1987-04-01 00:00:00
abstract::Neuropeptide Y and somatostatin immunoreactive neurons and processes were examined in human striatum using both immunofluorescence and avidin biotin immunoperoxidase methods. Reduced nicotinamide adenine dinucleotide phosphate diaphorase activity was histochemically determined by the reduction of nitro blue tetrazoliu...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90242-9
更新日期:1987-03-01 00:00:00
abstract::The work of Aguayo and colleagues [Aguayo, David and Bray (1981) J. Exp. Biol. 95, 231-240] demonstrates that grafts of peripheral neural tissue are able to induce regenerative elongation of cut axons in the adult central nervous system. Elucidation of the mechanism of this response requires an understanding of the ce...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90261-2
更新日期:1987-03-01 00:00:00
abstract::The topographic distribution of cells containing monoamine oxidase, the enzyme which deaminates amines, was studied in the cat medulla oblongata. By means of enzyme histochemistry using a new coupled peroxidation method, monoamine oxidase activity was demonstrated in the somata, dendrites and fibers. Type A monoamine ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90257-0
更新日期:1987-03-01 00:00:00
abstract::Oxytocin-binding sites were detected by autoradiography on rat brain sections incubated in the presence of the [3H]oxytocin. These sites were characterized pharmacologically using quantitative autoradiography. High pressure liquid chromatography controls of the incubation media indicated that labelling was due to the ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(87)90113-8
更新日期:1987-02-01 00:00:00